Bibliographic information
GuidelineWHO guidelines for malaria, 13 August 2025
Year of Publication2025
Issuing InstitutionWorld Health Organization
Recommendation
New
In areas with moderate to high levels of P. falciparum transmission, providing antimalarial medicine through mass drug administration (MDA) to reduce transmission is not recommended.
Recommended in favor
Conditional
Certainty of evidence
Very low
Notes and Remarks
Remarks
- The studies included in the systematic review did not demonstrate evidence that MDA has either a short- or long-term effect on P. falciparum transmission in moderate to high transmission settings.
- Recommendations on MDA to reduce the burden of malaria in moderate to high transmission settings can be found in section 4.2.4.1 MDA for burden reduction. Moderate to high transmission settings are defined as areas with P. falciparum parasite prevalence greater than 10%, or P. falciparum incidence above 250 cases per 1000 population per year [30]. These thresholds should not be regarded as absolutes for determining applicability of MDA.