Bibliographic information
GuidelineClinical management and infection prevention and control for mpox: living guideline, May 2025
Year of Publication2025
Issuing InstitutionWorld Health Organization
Recommendation
New
In patients with suspected or confirmed mpox infection, WHO suggests that health and care workers use contact and droplet precautions
Recommended in favor
Conditional
Certainty of evidence
Low
Notes and Remarks
- Consider using a respirator when the ventilation is poor or unknown or based upon a risk assessment (e.g. immunocompromised status or presence of mucosal lesions).• Airborne precautions should be implemented if varicella zoster virus (i.e. chickenpox) or measles are suspected and until they are excluded.
- Airborne precautions should be implemented when performing aerosolgenerating procedures (AGPs).
- If single rooms are not available or in limited supply, cohort confirmed patients and prioritize single rooms for suspect and probable patients.
Implementation considerations
- Contact and droplet precautions should be used by all health and care workers providing direct or indirect care (e.g. cleaning the environment, handling linen or waste) to patients with mpox.
- In addition to droplet and contact precautions, standard precautions should be followed for all patients at all times. The measures described below provide additional considerations for implementing droplet and contact precautions [7] in the context of mpox.
- Health and care workers should be trained in the use of standard and transmission-based precautions such as contact and droplet precautions and the proper use of PPE.