Ligne directrice

Risk reduction of cognitive decline and dementia: WHO guidelines, 2nd ed.

Année de publication

2026

Institution émettrice

World Health Organization

Liens

WHO IRIS

Recommandations

19 recommandations incluses

To reduce the risk of cognitive decline specifically, physical activity should be recommended to adults with normal cognition.

Statut

Maintenue

Recommandé en faveur

Forte

Certitude des données probantes

Modérée

To reduce the risk of cognitive decline specifically, physical activity may be recommended to adults with mild cognitive impairment.

Statut

Maintenue

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Faible

To reduce the risk of cognitive decline and dementia specifically, interventions for tobacco cessation should be offered to adults who use tobacco.

Statut

Maintenue

Recommandé en faveur

Forte

Certitude des données probantes

Faible

To reduce the risk of cognitive decline and/or dementia specifically, a healthy, balanced dietary pattern may be recommended to adults with normal cognition or mild cognitive impairment

Statut

Mise à jour

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Modérée

To reduce the risk of cognitive decline and/or dementia specifically, supplemention of vitamins B and E, omega-3 polyunsaturated fatty acids (PUFA) and multivitamins/ minerals is not recommended

Statut

Maintenue

Recommandé contre

Conditionnelle

Certitude des données probantes

Modérée

To reduce the risk of cognitive decline and/or dementia specifically, interventions aimed at reducing or ceasing hazardous and harmful drinking (including providing support to people with alcohol dependence) may be offered to adults with normal cognition or mild cognitive impairment.

Statut

Maintenue

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Modérée

To reduce the risk of cognitive decline and/or dementia specifically, cognitive training may be offered to older adults with normal cognition or mild cognitive impairment

Statut

Mise à jour

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Faible

To reduce the risk of cognitive decline and/or dementia specifically, engagement in social activity interventions may be recommended to adults with normal cognition or mild cognitive impairment.

Statut

Mise à jour

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Très faible

To reduce the risk of cognitive decline and/or dementia specifically, interventions for reducing midlife overweight or obesity may be offered

Statut

Mise à jour

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Faible

To reduce the risk of cognitive decline and/or dementia specifically, management of hypertension may be offered to adults with hypertension.

Statut

Mise à jour

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Très faible

To reduce the risk of cognitive decline and/or dementia specifically, management of diabetes may be offered to adults with diabetes.

Statut

Mise à jour

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Très faible

To reduce the risk of cognitive decline and/or dementia specifically, management of dyslipidaemia at midlife may be offered.

Statut

Maintenue

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Faible

To reduce the risk of cognitive decline and/or dementia specifically, hearing aids may be offered to adults with hearing loss.

Statut

Mise à jour

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Faible

To reduce the risk of cognitive decline and/or dementia specifically, engagement in cognitive stimulation may be encouraged.

Statut

Nouvelle

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Très faible

To reduce the risk of cognitive decline and/or dementia specifically, dietary restriction interventions may be offered to adults who are overweight or obese.

Statut

Nouvelle

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Faible

Menopausal hormone therapy is not recommended for specifically reducing the risk of cognitive decline and/or dementia in postmenopausal women aged 65 years and older.

Statut

Nouvelle

Recommandé contre

Conditionnelle

Certitude des données probantes

Très faible

Reducing exposure to household air pollution may reduce the risk or incidence of cognitive decline and/or dementia.

Statut

Nouvelle

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Très faible

Reducing exposure to ambient air pollution (especially PM2.5) may reduce the risk or incidence of cognitive decline and/or dementia.

Statut

Nouvelle

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Très faible

To reduce the risk of cognitive decline and/or dementia specifically, tailored, multidomain interventions may be offered.

Statut

Nouvelle

Recommandé en faveur

Conditionnelle

Certitude des données probantes

Modérée