Guía

WHO guidelines for the clinical management of filovirus disease

Año de publicación

2026

Institución emisora

World Health Organization

Enlaces

WHO IRIS

Recomendaciones

15 recomendaciones incluidas

WHO recommends that for patients with suspected or confirmed filovirus disease, systematic laboratory monitoring be performed based on clinical assessment, rather than on routine testing.

Estado

Nueva

Recomendado a favor

Fuerte

Certeza de la evidencia

Baja

WHO recommends patients with suspected or confirmed filovirus disease with ongoing gastrointestinal fluid losses and some dehydrationa be treated with a protocolized oral rehydration regimen (e.g. WHO Plan B).

Estado

Nueva

Recomendado a favor

Fuerte

Certeza de la evidencia

Moderada

WHO suggests patients with suspected or confirmed filovirus disease with ongoing gastrointestinal fluid losses and severe dehydrationa be treated with a protocolized intravenous fluid regimenb compared with no protocolized intravenous fluid regimen

Estado

Nueva

Recomendado a favor

Condicional

Certeza de la evidencia

Baja

WHO recommends balanced crystalloids (such as Ringer’s lactate) rather than 0.9% sodium chloride for acute intravenous fluid resuscitation in patients with suspected or confirmed filovirus disease.

Estado

Nueva

Recomendado a favor

Fuerte

Certeza de la evidencia

Moderada

WHO suggests for patients with suspected or confirmed filovirus disease and clinical signs of shock or circulatory impairment, the serial measurement of lactate as part of the assessment of perfusion to guide further intravenous fluid management.

Estado

Nueva

Recomendado a favor

Condicional

Certeza de la evidencia

Baja

WHO suggests for patients with suspected or confirmed filovirus disease and clinical signs of shock or circulatory impairment, capillary refill time should be used as part of the assessment of perfusion to guide intravenous fluid management

Estado

Nueva

Recomendado a favor

Condicional

Certeza de la evidencia

Baja

WHO suggests that for patients with suspected or confirmed filovirus disease with shock who are being resuscitated with intravenous fluids, vasopressor treatment be initiated early rather than later.

Estado

Nueva

Recomendado a favor

Condicional

Certeza de la evidencia

Baja

WHO recommends that patients with suspected or confirmed filovirus disease requiring a vasopressor be treated with norepinephrine rather than dopamine.

Estado

Nueva

Recomendado a favor

Fuerte

Certeza de la evidencia

Moderada

WHO suggests that patients with suspected or confirmed filovirus disease requiring a vasopressor be treated with norepinephrine rather than epinephrine.

Estado

Nueva

Recomendado a favor

Condicional

Certeza de la evidencia

Muy baja

WHO suggests that for patients with suspected or confirmed filovirus disease requiring initiation of vasopressors, peripheral intravenous catheters be used rather than central venous catheters.

Estado

Nueva

Recomendado a favor

Condicional

Certeza de la evidencia

Muy baja

WHO recommends that for patients with suspected or confirmed filovirus disease requiring central venous access, ultrasound guided placement be used rather than non-ultrasound guided placement.

Estado

Nueva

Recomendado a favor

Fuerte

Certeza de la evidencia

Moderada

WHO suggests for the use of presumptive broad-spectrum antibiotics in patients with confirmed filovirus disease in the presence of suspected sepsis or bacterial co-infection.

Estado

Nueva

Recomendado a favor

Condicional

Certeza de la evidencia

Baja

WHO suggests against the use of tranexamic acid in patients with confirmed filovirus disease and haemorrhage.

Estado

Nueva

Recomendado en contra

Condicional

Certeza de la evidencia

Muy baja

WHO suggests for the use of tranexamic acid in patients with confirmed filovirus disease and postpartum haemorrhage.

Estado

Nueva

Recomendado a favor

Condicional

Certeza de la evidencia

Baja

WHO recommends that persons who have survived/recovered from filovirus disease be offered structured follow-up after discharge.

Estado

Nueva

Recomendado a favor

Fuerte

Certeza de la evidencia

Moderada