Bibliographic information
GuidelineGuidelines on the treatment of skin and oral HIV-associated conditions in children and adults
Year of Publication2014
Issuing InstitutionWHO
Recommendation
New
(eosinophilic folliculitis ) Additional symptomatic therapy is recommended for the duration of the persistent symptoms with, depending on severity:
- oral antihistamine; if no adequate response, add
- topical corticosteroids (class 3, 4, 5 or 6, e.g. betamethasone valearate); if no adequate response, add
- oral itraconazole; if no adequate response, add
- permethrin 5% cream (applied above the waist)
Recommended in favor
Conditional
Certainty of evidence
Very low
Notes and Remarks
- 1)Drugs: Even though the quality of evidence is very low, betamethasone should be used if pruritus persists; if betamethasone is not available, other class 3, 4, 5 or 6 potent topical corticosteroids can be used instead.
- 2)Caution should be exercised in the use of oral antihistamines in young infants. Dosage should be adjusted by age and weight.
- 3)Itraconazole is excreted into human milk and therefore is not recommended for breastfeeding mothers. Cases of congenital abnormalities have been shown following itraconazole treatment