Bibliographic information
Recommendation
In inpatient settings, WHO strongly recommends using LF-LAM to assist in the diagnosis of active TB in HIV-positive adults, adolescents and children:
- with signs and symptoms of TB (pulmonary and/or
extrapulmonary) (strong recommendation, moderate certainty in the evidence about the intervention effects); or
- with advanced HIV disease; or
- who are seriously ill (strong recommendation, moderate
certainty in the evidence about the intervention effects); or
- irrespective of signs and symptoms of TB and with a CD4 cell
count <200 (strong recommendation, moderate certainty in the evidence about the intervention effects).
Recommended in favor
Strong
Certainty of evidence
Moderate
Also Featured In
This recommendation also appears in the following guidelines:
Lateral flow urine lipoarabinomannan assay (LF-LAM) for the diagnosis of active tuberculosis in people living with HIV: policy update 2019
WHO consolidated guidelines on tuberculosis: module 3: diagnosis – rapid diagnostics for tuberculosis detection: web annex 2. GRADE profiles