Bibliographic information

GuidelineWHO recommendations on antenatal corticosteroids for improving preterm birth outcomes.
Year of Publication2022
Issuing InstitutionWorld Health Organization

Recommendation

Maintained
Originally developed

Antenatal corticosteroid therapy is not recommended for women undergoing planned caesarean section at 34 weeks 0 days to 36 weeks 6 days

Not recommended

Notes and Remarks

REMARKS Q The GDG noted the paucity of evidence on the balance of benefits versus harms when antenatal corticosteroids are administered to women undergoing planned caesarean section (CS) at 34 weeks 0 days to 36 weeks 6 days gestation. The GDG acknowledged that, while there might be some benefits, there might also be harms. Reference was made to the overall evidence on antenatal corticosteroids, which included women undergoing provider-initiated (planned) preterm birth, and also suggested potential harms in late preterm infants. Q The GDG considered this to be a research priority but chose to recommend against the practice until further evidence becomes available. Q The GDG reaffirms that all pre-conditions outlined for antenatal corticosteroid therapy in Recommendation 1.0 apply.

Implementation considerations outlined in Table 2.

Also Featured In

This recommendation also appears in the following guidelines:

Guideline

WHO recommendations on maternal health: guidelines approved by the WHO Guidelines Review Committee, second edition. Geneva: World Health Organization; 2025

Year2023
InstitutionWorld Health Organization