Updated Recommendation
A new evidence synthesis was published:2025, WHO consolidated guidelines on tuberculosis: module 3: diagnosis
View latest version (2025)Bibliographic information
Recommendation
In adults with signs and symptoms of pulmonary TB and without a prior history of TB (≤5 years) or with a remote history of TB treatment (>5 years since end of treatment), Xpert Ultra should be used as an initial diagnostic test for TB and for rifampicin-resistance detection in sputum, rather than smear microscopy/culture and phenotypic DST.
Recommended in favor
Strong
Certainty of evidence
High
Also Featured In
This recommendation also appears in the following guidelines:
WHO consolidated guidelines on tuberculosis: module 3: diagnosis – rapid diagnostics for tuberculosis detection: web annex 2. GRADE profiles
WHO consolidated guidelines on tuberculosis: module 3: diagnosis – rapid diagnostics for tuberculosis detection: web annex 2. GRADE profiles