Bibliographic information
GuidelineGuidelines on the treatment of skin and oral HIV-associated conditions in children and adults
Year of Publication2014
Issuing InstitutionWHO
Recommendation
Maintained
Originally developed
In HIV-infected adults, adolescents and children diagnosed with severe symptomatic Kaposi sarcoma, immediate ART initiation in combination with systemic chemotherapy is recommended.
Recommended in favor
Strong
Certainty of evidence
Low
Notes and Remarks
- 1)Chemotherapy can also be considered if KS is progressive despite ART.
- 2)Whenever feasible, suspected KS lesions should be biopsied and diagnosis confirmed, especially before administration of chemotherapy.
- 4)All patients should be monitored for potential development of KS IRIS after ART initiation.
- 5)Chemotherapy drugs, especially those administered during the first trimester of pregnancy, may cause serious adverse fetal effects.
Also Featured In
This recommendation also appears in the following guidelines:
Guideline
WHO guidelines on the management of advanced HIV disease
Year2025
InstitutionWorld Health Organization