New Evidence Available
Updated Recommendation
A new evidence synthesis was published:2020, WHO consolidated guidelines on tuberculosis: tuberculosis preventive treatment: Module 1: prevention
View latest version (2020)Bibliographic information
GuidelineLatent tuberculosis infection: updated and consolidated guidelines for programmatic management
Year of Publication2018
Issuing InstitutionWHO
Recommendation
Retired
Rifampicin plus isoniazid daily for 3 months should be offered as an alternative to 6 months of isoniazid monotherapy as preventive treatment for children and adolescents aged < 15 years in countries with a high TB incidence
Recommended in favor
Strong
Certainty of evidence
Low
Notes and Remarks
Rifampicin- and rifapentine-containing regimens should be prescribed with caution to people living with HIV who are on ART because of potential drug–drug interactions.