New Evidence Available
Updated Recommendation
A new evidence synthesis was published:2024, Guidelines for the prevention, diagnosis, care and treatment for people with chronic hepatitis B infection.
View latest version (2024)Bibliographic information
GuidelineGuidelines for the prevention, care and treatment of persons with chronic hepatitis B infection
Year of Publication2015
Issuing InstitutionWorld Health Organization
Recommendation
Retired
CHRONIC HEPATITIS B. All persons with cirrhosis based on clinical evidence (or APRI score >2 in adults) require lifelong treatment with nucleos(t)ide analogues (NAs), and should not discontinue antiviral therapy because of the risk of reactivation, which can cause severe acute-on-chronic liver injury
Recommended in favor
Strong
Certainty of evidence
Low