New Evidence Available
Updated Recommendation
A new evidence synthesis was published:2020, WHO consolidated guidelines on tuberculosis: tuberculosis preventive treatment: Module 1: prevention
View latest version (2020)Bibliographic information
GuidelineLatent tuberculosis infection: updated and consolidated guidelines for programmatic management
Year of Publication2018
Issuing InstitutionWHO
Recommendation
Retired
Isoniazid monotherapy for 6 months is recommended for treatment of LTBI in both adults and children in countries with high and low TB incidence
Recommended in favor
Strong
Certainty of evidence
High
Notes and Remarks
Rifampicin- and rifapentine-containing regimens should be prescribed with caution to people living with HIV who are on ART because of potential drug–drug interactions.