Bibliographic information

GuidelineWHO recommendations for care of the preterm or low-birth-weight infant.
Year of Publication2022
Issuing InstitutionWorld Health Organization

Recommendation

New

Application of topical oil to the body of preterm or low-birthweight infants may be considered

Recommended in favor

Conditional

Notes and Remarks

Remarks

  • The recommendation is conditional on shared decision-making with parents; this includes informing parents about the benefits and risks and the need for further research.
  • The GDG noted that there were limited data on the type, dose, timing of initiation and duration of oil use. Based on most of the trials included in the evidence review, the GDG suggested that sunflower or coconut oils may be used and that initiation and duration of use may be based on clinical judgement. The GDG also felt that application of oils should be done gently to avoid disrupting skin integrity.
  • The GDG decided not to make a recommendation on the use of ointments or creams due to little or no effect on mortality and morbidity (invasive infection, necrotizing enterocolitis, bronchopulmonary dysplasia, retinopathy of prematurity) and no evidence on other critical outcomes.