Bibliographic information

GuidelineTherapeutics and COVID-19: living guideline, 10 November 2023.
Year of Publication2023
Issuing InstitutionWorld Health Organization

Recommendation

Maintained
Originally developed

We recommend against treatment with molnupiravir for patients with non-severe COVID-19 at low risk of hospitalization

Recommended against

Strong

Notes and Remarks

Remarks

  • See Section 6 regarding identifying patients at low risk.
  • The marginal benefits of molnupiravir for patients at low risk of hospitalization (those expected to have a 0.5% risk of hospital admission) suggest most patients would not want to use this treatment.
  • Given considerations regarding resources and equity, the GDG concluded that health care systems may reasonably not offer this drug to patients at low risk of hospitalization.

Also Featured In

This recommendation also appears in the following guidelines:

Guideline

Therapeutics and COVID-19: living guideline, August 2025

Year2025
InstitutionWorld Health Organization