New Evidence Available
Updated Recommendation
A new evidence synthesis was published:2025, WHO consolidated guidelines on tuberculosis: module 3: diagnosis
View latest version (2025)Bibliographic information
GuidelineWHO consolidated guidelines on tuberculosis: module 3: diagnosis: rapid diagnostics for tuberculosis detection, 3rd ed.
Year of Publication2024
Issuing InstitutionWorld Health Organization
Recommendation
Retired
In adults and children with signs and symptoms of pulmonary TB and a Truenat MTB or MTB Plus positive result, Truenat MTB-RIF Dx may be used as an initial test for rifampicin resistance rather than culture and phenotypic DST
Recommended in favor
Conditional
Certainty of evidence
Very low
Notes and Remarks
Remarks The Truenat aplies a reflex (two-step) test for rifampicin resistance. Hence, the recommendation for Truenat MTB-RIF Dx is only applicable for those patients with positive Truenat MTB or MTB Plus results.