Bibliographic information
Recommendation
We suggest not to use remdesivir for patients with critical COVID-19
Recommended against
Conditional
Notes and Remarks
Resources and other considerations Acceptability and feasibility Remdesivir is administered as one in travenous infusion daily over 10 consecutive days, and rather than in an outpa tient setting, this is more easily operationalized in hospitalized patients with critical disease. Obstacles to access in LMICs due to c ost, feasibility and availability are of concern (30). Challenges in shared decisionmaking and in c ommunicating the harms v ersus benefits of remdesivir may also be incr eased in LMICs.
Also Featured In
This recommendation also appears in the following guidelines:
Therapeutics and COVID-19: living guideline, 16 September 2022.
Therapeutics and COVID-19: living guideline, 10 November 2023.
Therapeutics and COVID-19: living guideline, August 2025