Bibliographic information
GuidelineWHO recommendations on adolescent health: guidelines approved by the WHO guidelines review committee
Year of Publication2017
Issuing InstitutionWorld Health Organization
Recommendation
New
In HIV-infected adults, adolescents and children diagnosed with mild/moderate Kaposi sarcoma, immediate ART initiation is recommended.
Recommended in favor
Strong
Certainty of evidence
Low
Notes and Remarks
- 1)Chemotherapy can also be considered if KS is progressive despite ART.
- 2)Whenever feasible, suspected KS lesions should be biopsied and diagnosis confirmed, especially before administration of chemotherapy.
- 4)All patients should be monitored for potential development of KS IRIS after ART initiation.
- 5)Chemotherapy drugs, especially those administered during the first trimester of pregnancy, may cause serious adverse fetal effects.