Bibliographic information
Recommendation
The World Health Organization (WHO) recommends against administering hydroxychloroquine or chloroquine for treatment of patients with COVID-19. This recommendation applies to patients with any disease severity and any duration of symptoms.
Recommended against
Strong
Certainty of evidence
Low
Notes and Remarks
Practical Info The GDG made a str ong recommendation against using h ydroxychloroquine or chloroquine for treatment of patients with COVID-19. The use o f hydroxychloroquine may preclude the use o f other important drugs that also prolong the Q T interval, such as azithromycin and fluoroquinolones. Concomitant use o f drugs that prolong the Q T interval should be done with e xtreme caution.
Also Featured In
This recommendation also appears in the following guidelines:
Therapeutics and COVID-19: living guideline, 17 December 2020.
Therapeutics and COVID-19: living guideline, 31 March 2021.
Therapeutics and COVID-19: living guideline, 6 July 2021.
Therapeutics and COVID-19: living guideline, 24 September 2021.
Therapeutics and COVID-19. Living guideline. 7 December 2021
Therapeutics and COVID-19: living guideline, 14 January 2022.
Therapeutics and COVID-19: living guideline, 3 March 2022.
Therapeutics and COVID-19: living guideline, 22 April 2022.
Therapeutics and COVID-19: living guideline, 14 July 2022.
Therapeutics and COVID-19: living guideline, 16 September 2022.
Therapeutics and COVID-19: living guideline, 10 November 2023.
Therapeutics and COVID-19: living guideline, August 2025