Bibliographic information

GuidelineWHO recommendations on antenatal corticosteroids for improving preterm birth outcomes.
Year of Publication2022
Issuing InstitutionWorld Health Organization

Recommendation

Maintained
Originally developed

Antenatal corticosteroid therapy is recommended for women with a high likelihood of preterm birth of a growth-restricted fetus

Context specific recommendation

Only in specific contexts

Notes and Remarks

REMARKS Q The GDG noted the limited evidence on the benefits of antenatal corticosteroids in this subgroup of women. However, the GDG placed its emphasis on the overall benefits of antenatal corticosteroids, the potential benefits in terms of reduced neurodevelopmental disability among surviving intrauterine growth-restricted infants, and evidence of reduced odds of adverse newborn mortality and morbidity outcomes. Q The GDG acknowledged that there are concerns about the effect of antenatal corticosteroids on fetal growth, but agreed that there is no evidence to suggest that corticosteroids will perform differently in this subgroup compared to the overall preterm population. Q The GDG reaffirms that all pre-conditions outlined for antenatal corticosteroid therapy in Recommendation 1.0 apply.

Implementation considerations outlined in Table 2.

Also Featured In

This recommendation also appears in the following guidelines:

Guideline

WHO recommendations on maternal health: guidelines approved by the WHO Guidelines Review Committee, second edition. Geneva: World Health Organization; 2025

Year2023
InstitutionWorld Health Organization