Bibliographic information
Recommendation
Antenatal corticosteroid therapy is recommended for women with a high likelihood of preterm birth of a growth-restricted fetus
Context specific recommendation
Only in specific contexts
Certainty of evidence
Very low
Notes and Remarks
REMARKS Q The GDG noted the limited evidence on the benefits of antenatal corticosteroids in this subgroup of women. However, the GDG placed its emphasis on the overall benefits of antenatal corticosteroids, the potential benefits in terms of reduced neurodevelopmental disability among surviving intrauterine growth-restricted infants, and evidence of reduced odds of adverse newborn mortality and morbidity outcomes. Q The GDG acknowledged that there are concerns about the effect of antenatal corticosteroids on fetal growth, but agreed that there is no evidence to suggest that corticosteroids will perform differently in this subgroup compared to the overall preterm population. Q The GDG reaffirms that all pre-conditions outlined for antenatal corticosteroid therapy in Recommendation 1.0 apply.
Implementation considerations outlined in Table 2.
Also Featured In
This recommendation also appears in the following guidelines:
WHO recommendations on maternal health: guidelines approved by the WHO Guidelines Review Committee, second edition. Geneva: World Health Organization; 2025