Guideline

The use of molecular line probe assays for the detection of resistance to second-line anti-tuberculosis drugs: policy guidance

Year of Publication

2016

Issuing Institution

WHO

Links

Google Scholar,WHO IRIS

Recommendations

2 included recommendations

For patients with confirmed rifampicin-resistant TB (tuberculosis) or MDR-TB (multidrug resistant tuberculosis), SL-LPA (Second-line lineprobe assays) may be used as the initial test, instead of phenotypic culture-based DST (drug-susceptibility testing), to detect resistance to fluoroquinolones

Status

Maintained

Recommended in favor

Conditional

Certainty of evidence

Low

For patients with confirmed rifampicin-resistant TB (tuberculosis) or MDR-TB (multidrug resistant tuberculosis), SL-LPA (Second-line lineprobe assays) may be used as the initial test, instead of phenotypic culture-based DST DST (drug-susceptibility testing), to detect resistance to the second-line injectable drugs

Status

Maintained

Recommended in favor

Conditional

Certainty of evidence

Very low