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Guideline

WHO consolidated guidelines on tuberculosis: module 3: diagnosis: tests for TB infection

Year of Publication
2022
Issuing Institution
WHO
Links
Google Scholar

Recommendations

3 included recommendations

interferon-gamma release assays tuberculosis interferon-gamma release assays (IGRAs) (and the TST) should not be used in low- and middle-income countries for the diagnosis of pulmonary or extra-pulmonary TB, nor for the diagnostic work-up of adults (including HIV-positive individuals) suspected of active TB in these settings (strong recommendation). This recommendation places a high value on avoiding the consequences of unnecessary treatment (high false-positives) given the low specificity of tuberculosis interferon-gamma release assays (IGRAs) (and the TST) in these settings.

Status
Maintained

Recommended against

Strong